EFFECT OF MADHUGHRITA YAPANAVASTHI IN TREATMENT OF LUMBAR SPONDYLOSIS

Lumbar spondylosis, a degenerative condition of lumbar spine is affecting majority of adults presently. The treatment options available nowadays are diverse and often undependable ensuing rising costs and variability in management throughout the country. It may be considered as Kateegraha owing to the grasping pain or stiffness in the Katee Pradesha. Katee is one of the Vatasthaanas and pain/stiffness is caused by Vata, hence Kateegraha may be considered as Vatavyadhi. Vasthi therapy is the Agryachikitsa for Vata Dosha which can be done here. Madhughrita Yapanavasthi is Vatahara, Brumhana and Trikaprishta Soolahara. It would be especially good in degenerative conditions associated with pain affecting Trika region like Lumbar spondylosis. The study design was of interventional type. Twenty patients, satisfying the selection criteria were selected from the OPD of Govt. Ayurveda College Panchakarma Hospital, Thiruvananthapuram. They were given Deepana Pachana first, and then Snehasweda and finally Madhughrita Yapanavasthi for 8 days while the follow up period were for 16 days. The assessment was done before treatment, after treatment and after follow up. Changes in the following variables- pain, stiffness, tenderness, range of movements and muscle strength were analyzed. For all variables except the muscle strength p value were statistically significant at the level of 0.001. The p value for Muscle strength was significant at the level of 0.05 for after treatment - after follow up comparison. And it was significant at the level of 0.01 for before treatment - after follow up comparison. Madhughrita Yapanavasthi is thus effective in managing Lumbar spondylosis

A Survey on the Pteridophyte Flora of the 18 Selected Sacred Groves in Chalavara Grama Panchayath, Palakkad District, Kerala

An exploratory survey conducted on Pteridophytic flora in the 18 selected sacred groves of Chalavara Grama panchayath, Ottapalamtaluk, Palakkad district, Kerala lead to the collection of 26 species of pteridophytes coming under 20 genera and 14 families. Among them, 02 families belongs to class Lycopsida, 01 family belongs to class Psilotopsida and remaining belongs to class Polypodiopsida. Out of 26 species 21 species are terrestrial, 3 species are epiphytes and 2 species are aquatic

A CONCEPTUAL APPRAISAL OF VIRECHANA KARMA

Panchakarma is getting global attention nowadays and Virechana is one among its procedures which is actively used by the Ayurvedic fraternity. Four different types of Virechana namely Anulomana, Sramsana, Bhedana and Rechana are mentioned in our classics but they are not apprised properly for their clinical utility. The Brihattrayis give ample illustrations of their use without highlighting the underlying rationale. Sarangdhara Samhita defines each of this therapeutics without indicating the disease conditions. This paper tries to understand the specific clinical utility of the four types of Rechana by tracing back their indications in scriptures. Anulomana is a mild form of Virechana where the Paka of Malas occur. Sramsana is a mild form of Virechana which does not cause Paka of Malas. Bhedana does not cause Paka of Malas but it is a strong type of Virechana. Rechana also does not cause Paka of mala but the strength of the procedure can be modulated by the use of different types of drugs. The selection of the type of Rechana depends on the pharmaco-therapeutic action necessary to harmonise the Dosa, Dhatu and Mala without causing any further complication or Upadrava

Novel Advent For Add-On Security By Magic Square Intrication

The efficiency of a cryptographic algorithm is based on its time taken for encryption / decryption and the way it produces diverse cipher text from a clear text. The RSA, the extensively used public key algorithm and other public key algorithms may not guarantee that the cipher text is copiously secured. As an alternative approach to handling ASCII characters in the cryptosystems, a magic square implementation is deliberated of in this work. It attempts to augment the efficiency by providing add-on security to the cryptosystem. This approach will boost the security due to its complexity in encryption because it deals with the magic square. Here, encryption / decryption is based on numerals generated by magic square rather than ASCII values. In this, we add the ASCII value and the numeral in the consequent magic square. Because to encrypt the plaintext characters, their ASCII values are taken and if a character occurs in numerous places in a plaintext there is a possibility of same cipher text is produced. To surmount the problem, this paper attempts to develop a technique in which a constant is added for the recurring character

Nursery rearing of Asian Seabass

Lates calcarifer species is widely distributed in the tropical and subtropical areas of the western Pacific and Indian ocean including Australia, Southeast Asia, the Philippines and countries bordering the Arabian sea. Seabass spend most of their life in a lagoon which connects to the sea. They spend two to three more years in estuarine areas until they mature, then migrate to the sea water around the mouth of a river or lagoon for spawning. Larvae and juveniles live in the sea grass bed in coastal areas for about six months, attaining a size of about 2 to 5 inches. The fish migrate to freshwater when they grow bigger

Gene Therapy in Cardiac Arrhythmias

Gene therapy has progressed from a dream to a bedside reality in quite a few human diseases. From its first application in adenosine deaminase deficiency, through the years, its application has evolved to vascular angiogenesis and cardiac arrhythmias. Gene based biological pacemakers using viral vectors or mesenchymal cells tested in animal models hold much promise. Induction of pacemaker activity within the left bundle branch can provide stable heart rates. Genetic modification of the AV node mimicking beta blockade can be therapeutic in the management of atrial fibrillation. G protein overexpression to modify the AV node also is experimental. Modification and expression of potassium channel genes altering the delayed rectifier potassium currents may permit better management of congenital long QT syndromes. Arrhythmias in a failing heart are due to abnormal calcium cycling. Potential targets for genetic modulation include the sarcoplasmic reticulum calcium pump, calsequestrin and sodium calcium exchanger. Lastly the ethical concerns need to be addressed

Antimicrobial efficacy and phytochemical analysis of Albizia amara (Roxb.) Boiv. an indigenous medicinal plant against some human and plant pathogenic bacteria and fungi

The present investigation evaluates the antimicrobial activity of six different solvent exts. and isolated constituents of leaves of Albizia amara against a total of 21 microorganisms which consisted of seven human pathogenic bacteria, a phytopathogenic Xanthomonas campestris (NCIM 2954) and thirteen seed-​borne phytopathogenic fungi. Our result showed that, among the six solvent exts. tested, the chloroform ext. showed a higher antibacterial and antifungal activity followed by methanol, ethanol and hydro-​methanolic exts. resp. The chloroform, methanol and ethanol exts. exhibited antibacterial activity with zone of inhibition ranging from 5.25 to 23.75, 6.25 to 23.25 and 7.25 to 22.7 mm resp. at 1mg​/mL concn. The minimal inhibitory concn. (MIC) of the chloroform ext. ranged from 15μg​/mL to 500μg​/mL depending upon bacterial species. The most susceptible organism in the present investigation was Streptococcus faecalis (NCIM 5025)​, while the most resistant was Proteus vulgaris (NCIM 2027)​. Highest antifungal activity was obsd. in chloroform ext. followed by methanol ext. with percent of inhibition ranging from 30​% to 77.4​% and 17.4​% to 71.7​% resp. The IC50 value of chloroform ext. ranged from 0.5mg​/mL to 5.0mg​/mL depending upon fungal species. Among the tested fungi, Fusarium lateratum was highly sensitive and Aspergillus flavus was least sensitive. Chloroform ext. was subsequently fractionated and monitored for antibacterial activity guided assay leading to the isolation of active fraction and was confirmed as alkaloid by further phytochem. anal. The present study thus confirms antimicrobial property of A. amara and also demonstrated the role of A. amara used in traditional medicine